Wounds in diabetic patients do not heal as rapidly as it would in a normal healthy individual. This leads to chronic non-healing wounds that can result in serious complications like amputations. Some wound dressings for diabetics are commercially available. However, they are very expensive. As the diabetic population in India keeps growing, treating these diabetic wounds will be a major clinical and social challenge.
Dr. Muthuvijayan and his team used a convex lens to focus sunlight on graphene oxide to obtain reduced graphene oxide. Then, they loaded these reduced graphene oxide dispersions into a solution of isabgol (psyllium) to obtain the wound dressing scaffolds. Fibroblast cells, responsible for wound healing were used to evaluate the toxicity and bioactivity of these scaffolds on cell attachment, migration and proliferation. The newly developed scaffolds were shown to provide a suitable tissue-friendly environment for the cells and subsequently improve cell proliferation and attachment.
Overall, the research showed that these wound dressings could significantly accelerate healing of both normal and diabetic wounds. The study has been done on rats where the normal wounds treated with the dressings healed in 16 days compared to 23 days in untreated wounds. Similarly, the wounds on diabetic rat treated with the dressings healed in 20 days compared to 26 days in untreated wounds. These scaffolds are easy to prepare, inexpensive, and show excellent healing properties.
A report on the research was published in a recent issue of Journal of Colloid and Interface Science.
Source: India Science Wire
Image: Isabgol Plant (For representative purpose only)